期刊: BIOCONJUGATE CHEMISTRY, 2021; 32 (5)
The overexpression of HIF-1 alpha in solid tumors due to hypoxia is closely related to drug resistance and consequent treatment failure. Herein, we co......
期刊: BIOCONJUGATE CHEMISTRY, 2021; 32 (4)
Brachytherapy has been clinically used for the treatment of malignant solid tumors. However, the classic therapeutic radioactive I-125 seed must be su......
期刊: BIOCONJUGATE CHEMISTRY, 2021; 32 (4)
Functionalized oligonucleotides (ONs) are widely applied as target binding molecules for biosensing and regulators for gene expression. Numerous effor......
期刊: BIOCONJUGATE CHEMISTRY, 2021; 32 (4)
Magnetic nanoparticles have been widely used for the separation of biomolecules for biological applications due to the mild and efficient separation p......
期刊: BIOCONJUGATE CHEMISTRY, 2021; 32 (5)
Polymeric small interfering RNA (siRNA) conjugate was elaborated to sequentially circumvent the predefined biological barriers encountered in the jour......
期刊: BIOCONJUGATE CHEMISTRY, 2021; 32 (6)
A cyclotriphosphazene-based "butterfly" fluorescence probe HCCP-MNI bearing two naphthalimide and morpholine units were developed for lysosome targeti......
期刊: BIOCONJUGATE CHEMISTRY, 2021; 32 (5)
In light of immune facilities trafficking toward the pathological sites along upward gradient of immunostimulatory cytokines, a localized resiquimod (......
期刊: BIOCONJUGATE CHEMISTRY, 2021; 32 (4)
As dental implants have become one of the main treatment options for patients with tooth loss, the number of patients with peri-implant diseases has i......
期刊: BIOCONJUGATE CHEMISTRY, 2021; 32 (8)
Antibody-drug conjugates (ADCs) have attracted great attention in recent years in the wake of an accelerated FDA approval rate and several large-scale......
期刊: BIOCONJUGATE CHEMISTRY, 2021; 32 (8)
Targeted radionuclide therapy (TRT) provides new and safe opportunities for cancer treatment and management with high precision and efficiency. Here w......
期刊: BIOCONJUGATE CHEMISTRY, 2021; 32 (8)
Hypoxia is a significant characteristic of tumors, which causes aggressive tumor growth and strong therapy resistance. Inspired by the improved therap......
期刊: BIOCONJUGATE CHEMISTRY, 2021; 32 (5)
SARS-CoV-2 caused the COVID-19 pandemic that lasted for more than a year. Globally, there is an urgent need to use safe and effective vaccines for imm......
期刊: BIOCONJUGATE CHEMISTRY, 2021; 32 (6)
Antibody-drug conjugates (ADCs) are complex pharmaceutical molecules that combine monoclonal antibodies with biologically active drugs through chemica......
期刊: BIOCONJUGATE CHEMISTRY, 2021; 32 (8)
Developing peptide tags that can bind target proteins covalently under mild conditions is of great importance for a myriad of applications, ranging fr......
期刊: BIOCONJUGATE CHEMISTRY, 2021; 32 (4)
Thioethers have been widely found in biologically active compounds, including pharmaceuticals. In this report, a highly efficient approach to on-DNA c......