期刊: EMBO REPORTS, 2021; 22 (6)
Mycobacterium tuberculosis (Mtb) has evolved various strategies to co-opt the host ubiquitin network to facilitate its proliferation. In the current i......
期刊: EMBO REPORTS, 2021; 22 (6)
Metabolic regulation is critical for the maintenance of pluripotency and the survival of embryonic stem cells (ESCs). The transcription factor Tfcp2l1......
期刊: EMBO REPORTS, 2021; 22 (7)
Tunneling nanotubes (TNTs) are actin-rich structures that connect two or more cells and mediate cargo exchange between spatially separated cells. TNTs......
期刊: EMBO REPORTS, 2021; 22 (8)
Zika virus (ZIKV) infection during pregnancy is linked to various developmental brain disorders. Infants who are asymptomatic at birth might have post......
期刊: EMBO REPORTS, 2021; 22 (8)
Snail is a dedicated transcriptional repressor and acts as a master inducer of EMT and metastasis, yet the underlying signaling cascades triggered by ......
期刊: EMBO REPORTS, 2021; 22 (7)
Dysregulation of lipid metabolism could lead to the development of metabolic disorders. We report here that the F-box protein JFK promotes excessive l......
期刊: EMBO REPORTS, 2021; 22 (7)
The development of the nervous system requires precise regulation. Any disturbance in the regulation process can lead to neurological developmental di......
期刊: EMBO REPORTS, 2021; 22 (6)
Pathological TDP-43 aggregation is characteristic of several neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS) and frontotempo......
期刊: EMBO REPORTS, 2021; 22 (6)
As the brain-resident innate immune cells, reactive microglia are a major pathological feature of Alzheimer's disease (AD). However, the exact role of......
期刊: EMBO REPORTS, 2021; 22 (7)
Receptor activator of NF-kappa B ligand (RANKL) is essential for osteoclast formation and bone remodeling. Nevertheless, the cellular source of RANKL ......
期刊: EMBO REPORTS, 2021; 22 (5)
Obesity has become a major health problem that has rapidly prevailed over the past several decades worldwide. Curcumin, a natural polyphenolic compoun......
期刊: EMBO REPORTS, 2021; 22 (8)
The type I interferon (IFN-I, IFN-alpha/beta)-mediated immune response is the first line of host defense against invading viruses. IFN-alpha/beta bind......
期刊: EMBO REPORTS, 2021; 22 (6)
Upon Mycobacterium tuberculosis (Mtb) infection, protein kinase G (PknG), a eukaryotic-type serine-threonine protein kinase (STPK), is secreted into h......
期刊: EMBO REPORTS, 2021; 22 (8)
TET methylcytosine dioxygenases are essential for the stability and function of regulatory T cells (Treg cells), which maintain immune homeostasis and......
期刊: EMBO REPORTS, 2021; 22 (8)
Several studies have examined the functions of nucleic acids in small extracellular vesicles (sEVs). However, much less is known about the protein car......