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NRSF deficiency leads to abnormal postnatal development of dentate gyrus and impairment of progenitors in subgranular zone of hippocampus

期刊: HIPPOCAMPUS, 2021; 31 (9)

Neuron-restrictive silencing factor (NRSF) is a zinc-finger transcription factor that regulates expression of a diverse set of genes. However, NRSF fu......

Sodium salicylate enhances neural excitation via reducing GABAergic transmission in the dentate gyrus area of rat hippocampus in vivo

期刊: HIPPOCAMPUS, 2021; 31 (5)

Sodium salicylate, one of the non-steroidal anti-inflammatory drugs, is widely prescribed in the clinic, but a high dose of usage can cause hyperactiv......

Role of the hippocampus in the spacing effect during memory retrieval

期刊: HIPPOCAMPUS, 2020; 30 (7)

It is well known that distributed learning (DL) leads to improved memory performance compared with massed learning (ML) (i.e., spacing effect). Howeve......

Interplay of the long axis of the hippocampus and ventromedial prefrontal cortex in schema-related memory retrieval

期刊: HIPPOCAMPUS, 2020; 30 (3)

When new information is relevant to prior knowledge or schema, it can be learned and remembered better. Rodent studies have suggested that the hippoca......

Downregulation of hyperpolarization-activated cyclic nucleotide-gated channels (HCN) in the hippocampus of patients with medial temporal lobe epilepsy and hippocampal sclerosis (MTLE-HS)

期刊: HIPPOCAMPUS, 2020; 30 (10)

Changes in the expression of HCN ion channels leading to changes inI(h)function and neuronal excitability are considered to be possible mechanisms inv......

The function of medial temporal lobe and posterior middle temporal gyrus in forming creative associations

期刊: HIPPOCAMPUS, 2020; 30 (12)

Although the function of the hippocampus and adjacent medial temporal lobe (MTL) areas in forming associations is generally recognized, how MTL contri......

Postnatal nectin-3 knockdown induces structural abnormalities of hippocampal principal neurons and memory deficits in adult mice

期刊: HIPPOCAMPUS, 2019; 29 (11)

The early postnatal stage is a critical period of hippocampal neurodevelopment and also a period of high vulnerability to adverse life experiences. Re......

JIF:3.27

Disruption of perineuronal nets increases the frequency of sharp wave ripple events

期刊: HIPPOCAMPUS, 2018; 28 (1)

Hippocampal sharp wave ripples (SWRs) represent irregularly occurring synchronous neuronal population events that are observed during phases of rest a......

JIF:3.27

Altered hippocampal GABA and glutamate levels and uncoupling from functional connectivity in multiple sclerosis

期刊: HIPPOCAMPUS, 2018; 28 (11)

There is growing evidence for dysfunctional glutamatergic excitation and/or gamma-aminobutyric acid (GABA)ergic inhibition in patients with multiple s......

JIF:3.27

A novel GLP-1/GIP/Gcg triagonist reduces cognitive deficits and pathology in the 3xTg mouse model of Alzheimer's disease

期刊: HIPPOCAMPUS, 2018; 28 (5)

Type 2 diabetes mellitus (T2DM) is an important risk factor for Alzheimer's disease (AD). Glucagon-like peptide-1 (GLP-1) and glucose-dependent insuli......

JIF:3.27

A novel antibody targeting sequence 31-35 in amyloid protein attenuates Alzheimer's disease-related neuronal damage

期刊: HIPPOCAMPUS, 2017; 27 (2)

Amyloid protein (A) plays a critical role in pathogenesis of Alzheimer's disease (AD). Our previous studies indicated that the sequence 31-35 in A mol......

JIF:3.97

Effect of a Hallucinogenic Serotonin 5-HT2A Receptor Agonist on Visually Guided, Hippocampal-dependent Spatial Cognition in C57BL/6J Mice

期刊: HIPPOCAMPUS, 2017; 27 (5)

By acting on serotonin 5-HT2A receptors (5-HT(2A)Rs), serotonergic psychedelic drugs induce perceptual and visual hallucinations by increasing neurona......

JIF:3.97

NSCs promote hippocampal neurogenesis, metabolic changes and synaptogenesis in APP/PS1 transgenic mice

期刊: HIPPOCAMPUS, 2017; 27 (12)

Adult neurogenesis and synaptic remodeling persist as a unique form of structural and functional plasticity in the hippocampal dentate gyrus (DG) and ......

JIF:3.97

Selforganization of modular activity of grid cells

期刊: HIPPOCAMPUS, 2017; 27 (11)

A unique topographical representation of space is found in the concerted activity of grid cells in the rodent medial entorhinal cortex. Many among the......

JIF:3.97

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