期刊: AGING AND DISEASE, 2022; 13 (4)
Existing diagnostic methods are limited to observing appearance and demeanor, even though genetic factors play important roles in the pathology of sch......
期刊: AGING AND DISEASE, 2022; 13 (6)
Diabetes mellitus (DM) and Parkinson's disease (PD) are both age-related diseases of global concern being among the most common chronic metabolic and ......
期刊: AGING AND DISEASE, 2022; 13 (2)
Population aging and the obesity epidemic are important global public health problems that pose an unprecedented threat to the physical and mental hea......
期刊: AGING AND DISEASE, 2022; 13 (1)
The circadian rhythm is an internal timing system, which is generated by circadian clock genes. Because the circadian rhythm regulates numerous cellul......
期刊: AGING AND DISEASE, 2022; 13 (2)
Sick, male, and older populations are more vulnerable to COVID-19. However, it remains unclear whether a common mechanism exists across different demo......
期刊: AGING AND DISEASE, 2022; 13 (1)
Aquaporin-4 (AQP4) is the most abundantly expressed aquaporin in the central nervous system (CNS) and is an integral part of the glymphatic system tha......
期刊: AGING AND DISEASE, 2022; 13 (2)
Dyslipidemia, characterized by a high level of lipids (cholesterol, triglycerides, or both), can increase the risk of developing and progressing ather......
期刊: AGING AND DISEASE, 2022; 13 (1)
Aging is a prominent risk factor for cardiovascular diseases, which is the leading cause of death around the world. Recently, cellular senescence has ......
期刊: AGING AND DISEASE, 2022; 13 (1)
Aging and hypertension are major risk factors for cerebral small vessel disease (CSVD). Anti hypertensive therapy has achieved effective; however, inc......
期刊: AGING AND DISEASE, 2022; 13 (1)
Ceramide is a core molecule of sphingolipid metabolism that causes selective insulin resistance and dyslipidemia. Research on its involvement in cardi......
期刊: AGING AND DISEASE, 2022; 13 (2)
Nucleus pulposus (NP) cell (NPC) senescence is one of the main causes of inters ertebral disc degeneration (IVDD). However, the underlying mechanism o......
期刊: AGING AND DISEASE, 2022; 13 (2)
Fibrosis is a pathological manifestation of wound healing that replaces dead/damaged tissue with collagen-rich scar tissue to maintain homeostasis, an......
期刊: AGING AND DISEASE, 2022; 13 (2)
Circular RNA (circRNA) is a recently discovered class of endogenous non-coding RNA that is generated by cyclization, driven by intron pairing, and reg......
期刊: AGING AND DISEASE, 2022; 13 (2)
The global increase in the aging population is expected to result in a shift from disease-centered to function-centered approaches in response to inte......