期刊： MOLECULAR PHARMACEUTICS, 2021; 18 (7)
Puerarin monohydrate (PUEM), as the commercial solid form of the natural anti-hypertension drug puerarin (PUE), has low solubility, poor flowability, ......
期刊： MOLECULAR PHARMACEUTICS, 2021; 18 (2)
Topical drug delivery has inherent advantages over other administration routes. However, the existence of stratum corneum limits the diffusion to smal......
期刊： MOLECULAR PHARMACEUTICS, 2021; 18 (4)
Berberine (BBR) is currently explored in the oral treatment of many disorders, especially in those involving inflammatory processes. Nanotechnology-ba......
期刊： MOLECULAR PHARMACEUTICS, 2021; 18 (7)
Functionalization of nanoparticles (NPs) with targeting moieties has a high potential to advance precision nanomedicine. However, the targeting moieti......
期刊： MOLECULAR PHARMACEUTICS, 2021; 18 (7)
The composites of amorphous vortioxetine (VXT) and ordered mesoporous silica were prepared. Three silica matrixes with different pore sizes were used ......
期刊： MOLECULAR PHARMACEUTICS, 2021; 18 (5)
Up to now, insufficient drug accumulation in tumor remains a major challenge for nanochemotherapy. However, the spherical nanocarriers with large diam......
期刊： MOLECULAR PHARMACEUTICS, 2021; 18 (5)
As a noninvasive therapy, high-intensity focused ultrasound (HIFU) shows great potential in inducing anticancer immune responses. However, the overall......
期刊： MOLECULAR PHARMACEUTICS, 2021; 18 (7)
Cancer metastasis is the major cause of cancer-related death; therefore, achieving suppression of tumor metastasis is a long-sought goal in cancer the......
期刊： MOLECULAR PHARMACEUTICS, 2021; 18 (7)
Increasing evidence has shown that nanocarriers have effects on several efflux drug transporters. To date, little is known about whether influx transp......
期刊： MOLECULAR PHARMACEUTICS, 2021; 18 (8)
Muscle atrophy usually occurs under mechanical unloading, which increases the risk of injury to reduce the functionality of the moving system, while t......
期刊： MOLECULAR PHARMACEUTICS, 2021; 18 (7)
Pancreatic cancer is a lethal malignancy with a dismal prognosis. Gemcitabine is currently used to treat pancreatic cancer, but it is limited by signi......
期刊： MOLECULAR PHARMACEUTICS, 2021; 18 (5)
Intestinal efflux transporters affect the gastrointestinal processing of many drugs but further data on their intestinal expression levels are require......
期刊： MOLECULAR PHARMACEUTICS, 2021; 18 (4)
To better promote the application of polymeric mixed micelles (PMMs), a coarse-grained molecular dynamics simulation (CGMD) has been employed to inves......
期刊： MOLECULAR PHARMACEUTICS, 2021; 18 (6)
Nanoparticle vaccine delivery systems have been emerging strategies for inducing potent immune responses to prevent and treat infectious diseases and ......
期刊： MOLECULAR PHARMACEUTICS, 2021; 18 (7)
Breast cancer was the leading cause of newly diagnosed cases of tumors in 2020, ranking as the second highest cause of female death. Chemotherapy rema......
