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The mitochondrial calcium uniporter engages UCP1 to form a thermoporter that promotes thermogenesis

Xue, KL; Wu, DM; Wang, YS; Zhao, YH; Shen, HY; Yao, JF; Huang, X; Li, XM; Zhou, Z; Wang, ZH; Qiu, YF

Qiu, YF (通讯作者),Peking Univ, Inst Mol Med, Coll Future Technol, Beijing Key Lab Cardiometab Mol Med, Beijing 100871, Peoples R China.;Qiu, YF (通讯作者),Peking Univ, Peking Tsinghua Ctr Life Sci, Beijing 100871, Peoples R China.

CELL METABOLISM, 2022; 34 (9): 1325

Abstract

Uncoupling protein 1 (UCP1)-mediated adaptive thermogenesis protects mammals against hypothermia and metabolic dysregulation. Whether and how mitochon......

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