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Advances and Insights of APC-Asef Inhibitors for Metastatic Colorectal Cancer Therapy

Yang, XY; Zhong, J; Zhang, QF; Feng, L; Zheng, Z; Zhang, J; Lu, SY

Yang, XY; Zhang, J; Lu, SY (corresponding author), Shanghai Jiao Tong Univ, Sch Med, Key Lab Cell Differentiat & Apoptosis, Dept Pathophysiol,Chinese Minist Educ, Shanghai, Peoples R China.; Zhang, J; Lu, SY (corresponding author), Shanghai Jiao Tong Univ, Sch Med, Med Chem & Bioinformat Ctr, Shanghai, Peoples R China.

FRONTIERS IN MOLECULAR BIOSCIENCES, 2021; 8 ():

Abstract

In Colorectal cancer (CRC), adenomatous polyposis coli (APC) directly interacts with the Rho guanine nucleotide exchange factor 4 (Asef) and releases ......

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