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type=1, lengthMark=0), GetTopicListResponse(id=2120732, encodeId=3a7c2120e324c, content=这项研究工作通过分离<a href='/topic/show?id=ab181056e1da' target=_blank style='color:#2F92EE;'>#雌二醇降解菌#</a>，发现了肠道菌Klebsiella aerogenes（<a href='/topic/show?id=c4751056e25c' target=_blank style='color:#2F92EE;'>#产气克雷伯氏菌#</a>）表达的3β-HSD能导致宿主血清<a href='/topic/show?id=60ea98e5030' target=_blank style='color:#2F92EE;'>#雌二醇#</a>降低和<a href='/topic/show?id=0a0b5496306' target=_blank style='color:#2F92EE;'>#抑郁#</a>样行为。这是极有意思的。肠道细菌能降低雌激素，竟然还是产气克雷伯氏菌！事实上，去年Science Translational Medicine发表的一项研究表明，在部分<a href='/topic/show?id=b0bc81566c8' target=_blank style='color:#2F92EE;'>#肠易激综合征#</a>（IBS）患者中，<a href='/topic/show?id=6ebc81e3482' target=_blank style='color:#2F92EE;'>#肠道菌群#</a>是<a href='/topic/show?id=a830e7734a0' target=_blank style='color:#2F92EE;'>#组胺#</a>的重要来源，特定的产气克雷伯菌则是主要“嫌犯”。意味着产气克雷伯菌可能扮演很多角色，既可能是IBS的诱因之一，也可能是诱导抑郁，同时也是<a href='/topic/show?id=4ed86115639' target=_blank style='color:#2F92EE;'>#机会性感染#</a>的重要致病菌。但是，有矛必有盾，肠道中哪些细菌扮演有益的角色？<a href='/topic/show?id=5d0ee2249b0' target=_blank style='color:#2F92EE;'>#益生菌#</a>, objectTitle=Cell子刊：武汉大学李艳/王高华/刘忠纯揭示肠道细菌引起女性抑郁症的潜在机理, objectType=article, longId=763473, objectId=575ee634733d, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/Random/doctor-writing-D3K6QME.jpg, objectUrl=/article/show_article.do?id=575ee634733d, replyNumber=0, likeNumber=182, createdTime=2023-03-21, rootId=0, userName=侠胆医心, userId=f63e4754896, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=上海, moduleDTOList=[ModuleDTO(moduleId=575ee634733d, moduleTitle=Cell子刊：武汉大学李艳/王高华/刘忠纯揭示肠道细菌引起女性抑郁症的潜在机理, moduleType=article, hrefUrl=//www.sandwebs.com/article/show_article.do?id=575ee634733d)], followStatus=false, userIsMember=false, type=1, lengthMark=1), GetTopicListResponse(id=1742171, encodeId=e4c81e42171c0, content=<a href='/topic/show?id=a830e7734a0' target=_blank style='color:#2F92EE;'>#组胺#</a>, 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组胺

2020-05-29

梅斯管理员 (审核中...)

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#组胺# #发作性睡病# #替洛利生# #日间过度嗜睡# #猝倒#

好文推荐 | 替洛利生治疗中国发作性睡病患者有效性及安全性的研究

2024-04-18发表于陕西省

bluefate133 (审核中...)

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#组胺#

JAMA子刊：苯二氮卓或抗组胺药对急性眩晕症患者的疗效

2023-02-16

侠胆医心 (审核中...)

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全文收起这项研究工作通过分离#雌二醇降解菌#，发现了肠道菌Klebsiella aerogenes（#产气克雷伯氏菌#）表达的3β-HSD能导致宿主血清#雌二醇#降低和#抑郁#样行为。这是极有意思的。肠道细菌能降低雌激素，竟然还是产气克雷伯氏菌！事实上，去年Science Translational Medicine发表的一项研究表明，在部分#肠易激综合征#（IBS）患者中，#肠道菌群#是#组胺#的重要来源，特定的产气克雷伯菌则是主要“嫌犯”。意味着产气克雷伯菌可能扮演很多角色，既可能是IBS的诱因之一，也可能是诱导抑郁，同时也是#机会性感染#的重要致病菌。但是，有矛必有盾，肠道中哪些细菌扮演有益的角色？#益生菌#

Cell子刊：武汉大学李艳/王高华/刘忠纯揭示肠道细菌引起女性抑郁症的潜在机理

2023-03-21发表于上海

bluefate133 (审核中...)

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#组胺#

抗组胺药物除了用于过敏性疾病，其他“角色”知多少

2022-10-29

bluefate133 (审核中...)

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#组胺#

JCO：H1-抗组胺药可降低HBV、HCV或HBV-HCV合并感染患者患肝细胞癌的风险

2022-05-12

bluefate133 (审核中...)

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#组胺#

JAHA：绝经后妇女组胺H2受体拮抗剂与心力衰竭风险之间的关系

2022-11-10

bluefate133 (审核中...)

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#组胺#

Nat Med：非布替尼治疗H1抗组胺药难治性慢性自发性荨麻疹

2022-07-15

bluefate133 (审核中...)

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#组胺#

JAAD:抗组胺药物联合局部皮质类固醇和表面冷冻治疗斑秃的疗效分析

2022-02-23

bluefate133 (审核中...)

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#组胺#

Am J Gastr: 质子泵抑制剂与组胺 2 受体拮抗剂对胃癌的发生风险均没有特殊影响

2021-12-21

bluefate133 (审核中...)

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#组胺#

Allergy Asthma Clin Immunol：白三烯受体拮抗剂与选择性H1-抗组胺药治疗过敏性鼻炎：当前证据的元分析

2022-03-10

bluefate133 (审核中...)

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#组胺#

Cornea：抗组胺药物释放隐形眼镜可用于治疗眼部过敏性瘙痒

2021-04-12

bluefate133 (审核中...)

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#组胺#

Ann Allergy Asthma Immunol：鼻内抗组胺治疗过敏性鼻炎要优于口服H1抗组胺

2021-04-08

bluefate133 (审核中...)

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#组胺#

Brit J Cancer：质子泵抑制剂和组胺-2受体拮抗剂与胃癌风险

2021-03-30

bluefate133 (审核中...)

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#组胺#

BMJ：质子泵抑制剂和组胺受体拮抗剂对胃肠道出血的预防效果

2020-05-12

bluefate133 (审核中...)

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#组胺#

抗组胺药物不止引起嗜睡，还需注意这些！

2020-11-17

bluefate133 (审核中...)

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#组胺#

Am J Rhinol Allergy：鼻腔类固醇和抗组胺剂使用对总氧化应激和抗氧化状态的影响

2021-06-11

bluefate133 (审核中...)

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#组胺#

Brit J Cancer：H1抗组胺药在对侧乳腺癌中的作用

2020-08-04

bluefate133 (审核中...)

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#组胺#

抗组胺药治疗婴幼儿过敏性鼻炎的临床应用专家共识

2020-01-26

bluefate133 (审核中...)

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#组胺#

Clin Exp Pharmacol Physiol：淫羊藿苷能够抑制组胺诱导的鼻粘膜上皮细胞炎症细胞因子和粘蛋白的表达

2019-11-15

bluefate133 (审核中...)

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#组胺#

Artif Cells Nanomed Biotechnol：组胺H1型受体（H1R）在调节成骨细胞分化和矿化中的作用

2019-08-18

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